Scientific Publications

Enternally Administered LB1148, A Serine Protease Inhibitor, Results In Significantly Faster Return Of Gut Function Compared To Placebo In Rats Undergoing Laporatomy And Bowel Resection/Anastamosis

Leading BioSciences poster presentation at 4th Enhanced Recovery After Surgery (ERAS) World Congress, Lisbon, Portugal
April 28, 2016

Autodigestion: Proteolytic Degradation and Multiple Organ Failure in Shock
November 25, 2015

Postoperative Ileus: Recent Developments in Pathophysiology and Management
Clinical Nutrition
June 2015; Volume 34, Issue 3

Impact of Postsurgical Opioid Use and Ileus on Economic Outcomes in Gastrointestinal Surgeries
Current Medical Research and Opinion (CMRO)
April 2015; Volume 31, Issue 4

Postoperative Complications and Mortality After Major Gastrointestinal Surgery
June 27, 2014; Volume 50, Issue 2

The Autodigestion Hypothesis for Shock and Multi-Organ Failure
Annals of Biomedical Engineering
February 2014; Volume 42, Issue 2

Pancreatic Digestive Enzyme Blockade in the Intestine Increases Survival After Experimental Shock
Science Translational Medicine
January 23, 2013; Volume 5, Issue 169

2008 Landis Award Lecture Inflammation and the Autodigestion Hypothesis
May 2009; Volume 16, Issue 4

A New Hypothesis for Microvascular Inflammation in Shock and Multiorgan Failure: Self-Digestion by Pancreatic Enzymes
January-February 2005; Volume 12, Issue 1