Scientific Publications

Pooled-Analysis of Incidence and Severity of Post-Surgical Intraabdominal Adhesions following Bowel Resection Surgery and Treatment with Enteral Protease Inhibitor LB1148

Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) 2022, The Next Big Thing
March 16, 2022

Enternally Administered LB1148, A Serine Protease Inhibitor, Results In Significantly Faster Return Of Gut Function Compared To Placebo In Rats Undergoing Laporatomy And Bowel Resection/Anastamosis

Leading BioSciences poster presentation at 4th Enhanced Recovery After Surgery (ERAS) World Congress, Lisbon, Portugal
April 28, 2016

Autodigestion: Proteolytic Degradation and Multiple Organ Failure in Shock
November 25, 2015

Postoperative Ileus: Recent Developments in Pathophysiology and Management
Clinical Nutrition
June 2015; Volume 34, Issue 3

Impact of Postsurgical Opioid Use and Ileus on Economic Outcomes in Gastrointestinal Surgeries
Current Medical Research and Opinion (CMRO)
April 2015; Volume 31, Issue 4

Postoperative Complications and Mortality After Major Gastrointestinal Surgery
June 27, 2014; Volume 50, Issue 2

The Autodigestion Hypothesis for Shock and Multi-Organ Failure
Annals of Biomedical Engineering
February 2014; Volume 42, Issue 2

Pancreatic Digestive Enzyme Blockade in the Intestine Increases Survival After Experimental Shock
Science Translational Medicine
January 23, 2013; Volume 5, Issue 169

2008 Landis Award Lecture Inflammation and the Autodigestion Hypothesis
May 2009; Volume 16, Issue 4

A New Hypothesis for Microvascular Inflammation in Shock and Multiorgan Failure: Self-Digestion by Pancreatic Enzymes
January-February 2005; Volume 12, Issue 1